The Role of Addition of Vitamin C in Iron Supplementation on Ferritin Serum Levels in Anemia Adolescent Females

  • Nanik Dwi Astuti Airlangga University
  • Bambang wirjatmadi
  • Merryana Adriani


Prevention of iron deficiency anemia in Indonesia using ferrous sulfas blood-added tablets started since 1997. But iron deficiency anemia is still high, also in young women. Young women are vulnerable because of rapid growth and unhealthy their consumption patterns, which rarely consume fruits and vegetables that are a source of vitamin C. The purpose of this study was to analyze the addition of vitamin C in iron supplementation + folic acid to serum ferritin levels in adolescents females anemia. This research is an experimental quasi research. Design research Randomized Pre Post Test Control Group Design, with Double Blind treatment. This study has one treatment group and one control group, each group of 11 samples. The samples were chosen randomly with inclusion and exclusion. The collected data was processed using SPSS program with the analysis of paired t-test and independent t-test to test the difference of serum ferritin level. The results showed the characteristics of respondents: age (p = 0.430), education of mother (p = 0.942) and nutritional knowledge of respondents (p = 0.928) in the same condition or both groups in homogeneous characteristics. The pattern and level of food consumption showed no different between groups (p> 0.05). Serum ferritin levels after treatment showed difference between the two groups (p = 0.004). This shows that vitamin C had a role in increasing iron absorption and fill in storage of ferritin formation.

Keywords: anemia, vitamin C, iron supplement, serum ferritin


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Mar 25, 2018
How to Cite
ASTUTI, Nanik Dwi; WIRJATMADI, Bambang; ADRIANI, Merryana. The Role of Addition of Vitamin C in Iron Supplementation on Ferritin Serum Levels in Anemia Adolescent Females. Health Notions, [S.l.], v. 2, n. 3, mar. 2018. ISSN 2580-4936. Available at: <>. Date accessed: 21 july 2018.
Research Article