Effect of Probiotic Milk containing L. casei Shirota on Immunoglobulin G Levels among Anemic Adolescent Girls

Elya Sugianti, Annis Catur Adi, Ikeu Ekayanti, Trias Mahmudiono, Widati Fatmaningrum, Siti Nur Husnul Yusmiati

Abstract


Probiotic play important role on immune systems. This study was to investigate effect of probiotic milk containing L. casei Shirota on immunoglobulin G levels among anemic adolescent girls. A total of 22 adolescent girls aged 13-18 years with anemia were included on this study. The subjects were separated into 2 groups i.e. a probiotic group and a control group by simple random sampling. During 4 weeks, a probiotic group received 1 tablet of 60 Fe elemental + 250 µg folate acid once a week and probiotic milk once daily. While a control group received 1 tablet of 60 Fe elemental + 250 µg folate acid once a week. Blood samples were collected at 0 and 4 weeks and assayed for immunoglobulin G levels by ELISA. Immunoglobulin G levels were not significantly increase after intervention. Compared with control group, probiotic milk administration in probiotic group did not significantly increased immunoglobulin G levels (p>0.05). The probiotic milk containing L. casei Shirota did not improve immunoglobulin G levels on anemic adolescent girls.
Keywords: Probiotic, Immunoglobulin G levels, Anemia, Adolescent girls


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DOI: https://doi.org/10.33846/hn.v2i2.138

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Copyright (c) 2018 Elya Sugianti, Annis Catur Adi, Ikeu Ekayanti, Trias Mahmudiono, Widati Fatmaningrum, Siti Nur Husnul Yusmiati

"HEALTH NOTIONS" ISSN: 2580-4936 (online version only), published by Humanistic Network for Science and Technology    

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